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Characterizing and treating pulmonary pathology in...
Journal article

Characterizing and treating pulmonary pathology in Marfan syndrome (847.2)

Abstract

Marfan syndrome (MFS) is a connective tissue disorder that leads to life‐threatening complications. While current research focuses on the cardiovascular pathogenesis of MFS, MFS also gives rise to serious pulmonary disease, the study of which is severely lacking. Therefore, we aimed to characterize lung function in a murine model of MFS and investigate the pharmacological effectiveness of Losartan, an angiotensin II receptor type I blocker, and …

Authors

Sellers S; Chan R; Hirota J; Mielnik M; Hogg J; Bernatchez P

Journal

The FASEB Journal, Vol. 28, No. S1,

Publisher

Wiley

Publication Date

April 2014

DOI

10.1096/fasebj.28.1_supplement.847.2

ISSN

0892-6638