Journal article
Hypocalcemia Risk of Denosumab Across the Spectrum of Kidney Disease: A Population‐Based Cohort Study
Abstract
Denosumab can be used in patients with chronic kidney disease (CKD) but has been linked with cases of severe hypocalcemia. The incidence of and risk factors for hypocalcemia after denosumab use are not well established. Using linked health care databases at ICES, we conducted a population-based cohort study of adults >65 years old with a new prescription for denosumab or a bisphosphonate between 2012 and 2020. We assessed incidence of …
Authors
Cowan A; Jeyakumar N; McArthur E; Fleet JL; Kanagalingam T; Karp I; Khan T; Muanda FT; Nash DM; Silver SA
Journal
Journal of Bone and Mineral Research, Vol. 38, No. 5, pp. 650–658
Publisher
Oxford University Press (OUP)
Publication Date
December 1, 2020
DOI
10.1002/jbmr.4804
ISSN
0884-0431