METRNL Rescues Glucose Intolerance and Ameliorates Obesity Phenotype in a Diet‐Induced Model of Obesity

Physical inactivity is a primary modifiable risk factor for obesity and type 2 diabetes (T2D), metabolic diseases that are rampant in both pediatric/adult populations. Endurance exercise has been shown to prevent/attenuate the onset and progression of obesity/T2D. We postulated that exercise mediated these pro‐metabolic effects on distal fat depots and other organs via secretory myokines. Our lab has identified two such myokines: interleukin‐15 …