Journal article
A67 RAPID REDUCTION IN ANXIETY SCORES IN IBD PATIENTS AFTER INFLIXIMAB INFUSION IS ASSOCIATED WITH CHANGES IN KYNURENINE/TRYPTOPHAN METABOLISM
Abstract
Patients with inflammatory bowel disease (IBD) frequently suffer from psychiatric comorbidities, mainly anxiety and depression. Infliximab, an anti-TNFα antibody, is commonly used for treatment of colitis. There are anecdotal reports of IBD patients having improvement in mood only hours after infliximab infusion, well before intestinal mucosal healing could occur. To evaluate the immediate effects of infliximab infusion on intestinal and …
Authors
Seiler C; Avila C; Khana R; Springer E; James C; Armstrong D; Marshall J; Collins SM; Pinto-Sanchez MI; Bercik P
Journal
Journal of the Canadian Association of Gastroenterology, Vol. 1, No. suppl_2, pp. 106–106
Publisher
Oxford University Press (OUP)
Publication Date
March 1, 2018
DOI
10.1093/jcag/gwy009.067
ISSN
2515-2084