Journal article
Involvement of Caveolin-1 in CD83 Internalization in Mouse Dendritic Cells
Abstract
To become potent T-cell stimulators, DCs need to mature. Treatment with soluble CD83 (sCD83) induces immune tolerance and protects against transplant rejection by maintaining dendritic cells in an immature, tolerogenic state. Until now, the mechanism through which sCD83 keeps DCs immature has not been investigated. The internalizing pathway of CD83 was screened by Western blot, and the direct interactions between internalized proteins were …
Authors
Yang Y; Xin Z; Chu J; Li N; Sun T
Journal
Cell Transplantation, Vol. 24, No. 7, pp. 1395–1404
Publisher
SAGE Publications
Publication Date
July 2015
DOI
10.3727/096368914x682116
ISSN
0963-6897