Journal article
Mucoadhesive thermogel platform for treating anterior ocular conditions
Abstract
A platform mucoadhesive and thermogelling eyedrop was developed for application to the inferior fornix for the treatment of various anterior segment ocular conditions. The poly(n-isopropylacrylamide) polymers (pNIPAAm), containing a disulfide bridging monomer, were crosslinked with chitosan to yield a modifiable, mucoadhesive, and natively degradable thermogelling system. Three different conjugates were studied including a small molecule for …
Authors
Ross M; Sheardown L; Muirhead B; Mofford J; Tian J; Sheardown H
Journal
Journal of Biomedical Materials Research Part A, Vol. 111, No. 9, pp. 1390–1405
Publisher
Wiley
Publication Date
September 2023
DOI
10.1002/jbm.a.37541
ISSN
1549-3296