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Influence of zinc and zinc chelator on HT-29...
Journal article

Influence of zinc and zinc chelator on HT-29 colorectal cell line

Abstract

Trace elements are involved in many key pathways involving cell cycle control. The influence of zinc and zinc chelator (TPEN) on transcription levels of the main zinc transporters (ZnT1 and ZIP1) in the HT-29 colorectal cell line has not been reported. Proliferation of HT-29 cells was measured using the methylene blue assay after exposure to zinc (two concentrations), TPEN (two concentrations), or a combination of zinc and TPEN (simultaneously …

Authors

Gurusamy KS; Farooqui N; Loizidou M; Dijk S; Taanman JW; Whiting S; Farquharson MJ; Fuller BJ; Davidson BR

Journal

BioMetals, Vol. 24, No. 1, pp. 143–151

Publisher

Springer Nature

Publication Date

February 2011

DOI

10.1007/s10534-010-9382-5

ISSN

0966-0844