Endurance exercise training increases medullary and extramedullary hematopoiesis

Increases in hematocrit are a well known adaptation to exercise training. It is not known if exercise training induces changes in hematopoietic tissues that facilitate increases in hematocrit. The colony forming unit GEMM assay was used to assess the effects of ten weeks of progressive treadmill training on the hematopoietic progenitor content in several tissues of four week old C57Bl/6 mice. Red blood cell progenitors increased by 3.1, 4.7, …