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A direct synthesis of functionalized styrenes and...
Journal article

A direct synthesis of functionalized styrenes and terminal 1,3-dienes via aqueous Wittig chemistry with formalin

Abstract

A direct synthesis of functionalized styrenes including synthetically valuable styryl halides and terminal 1,3-dienes is reported directly from benzylic and allylic alcohols and aqueous formalin involving microwave assisted phosphonium salt formation and Wittig olefination under mildly basic conditions.

Authors

Das P; McLeod D; McNulty J

Journal

Tetrahedron Letters, Vol. 52, No. 2, pp. 199–201

Publisher

Elsevier

Publication Date

January 2011

DOI

10.1016/j.tetlet.2010.10.090

ISSN

0040-4039