Journal article
Heck reactions of aryl halides in phosphonium salt ionic liquids: library screening and applications
Abstract
The Heck cross-coupling of aryl iodides and bromides with olefins proceeds in the phosphonium salt ionic liquid trihexyl(tetradecyl)phosphonium chloride (THP-Cl) in excellent yields. Furthermore, it is shown that the counter anion matched to the phosphonium cation exerts a measurable effect on the overall yield.
Authors
Gerritsma DA; Robertson A; McNulty J; Capretta A
Journal
Tetrahedron Letters, Vol. 45, No. 41, pp. 7629–7631
Publisher
Elsevier
Publication Date
October 2004
DOI
10.1016/j.tetlet.2004.08.103
ISSN
0040-4039