Journal article
Dimethylmalonyltrialkylphosphoranes: probing the steric effect on phosphorus and its stereochemical consequence in esterification reactions of chiral secondary alcohols
Abstract
High chemical yields and high levels of stereochemical inversion are demonstrated in the phosphorane-mediated esterification reaction of chiral alcohols with non-hindered carboxylic acids through the incorporation of sterically non-hindered alkyl groups of phosphorus.
Authors
Dyck J; Zavorine S; Robertson AJ; Capretta A; Larichev V; Britten J; McNulty J
Journal
Journal of Organometallic Chemistry, Vol. 690, No. 10, pp. 2548–2552
Publisher
Elsevier
Publication Date
May 2005
DOI
10.1016/j.jorganchem.2004.10.046
ISSN
0022-328X