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Abstract P2-02-04: De-escalation of bone-targeted...
Journal article

Abstract P2-02-04: De-escalation of bone-targeted treatment: Does the number of 6-monthly adjuvant zoledronate infusions received affect treatment efficacy for early breast cancer? A sub-study of ABCSG-12

Abstract

Abstract Background: The results of the Early Breast Cancer Trialist Group (EBCTCG) meta-analysis (Lancet 2015) led to the widespread adoption of bisphosphonates as adjuvant therapy for postmenopausal early-stage breast cancer (EBC). Despite evaluating multiple bisphosphonate agents and regimens, there was no signal of varying efficacy with different agents, routes of administration or dose/dose intensity. We evaluated the …

Authors

Beltran-Bless A-A; Clemons M; Fesl C; Hlauschek D; Soelkner L; Pond GR; Vandermeer L; Greil R; Balic M; Bjelic-Radisic V

Journal

Cancer Research, Vol. 83, No. 5_Supplement,

Publisher

American Association for Cancer Research (AACR)

Publication Date

March 1, 2023

DOI

10.1158/1538-7445.sabcs22-p2-02-04

ISSN

0008-5472