Journal article
Multilevel computations of dispersed drug release
Abstract
Abstract We study a mathematical model of drug release from controlled delivery systems with initial drug loading higher than solubility. The model combines dissolution, diffusion, swelling, and erosion mechanisms of drug delivery. Multilevel methods are introduced to solve the governing system of diffusion equations numerically with better accuracy and lower computational costs compared with the finite element methods. Numerical examples are …
Authors
Zhao W; Pelinovsky DE
Journal
Numerical Methods for Partial Differential Equations, Vol. 29, No. 4, pp. 1391–1415
Publisher
Wiley
Publication Date
July 2013
DOI
10.1002/num.21761
ISSN
0749-159X