Journal article
Patients With Crohn's Disease and Permanent Ileostomy Are Universally Excluded From Clinical Trials: A Systematic Review
Abstract
INTRODUCTION: We performed a systematic review to investigate whether patients with Crohn's disease (CD) and permanent ileostomy (PI) have been included in clinical trials evaluating biologics and small molecules.
METHODS: MEDLINE, Embase and Cochrane library (CENTRAL) data bases were searched from inception to May 16, 2022 for placebo controlled induction and/or maintenance randomized controlled trials assessing biologics and oral small …
Authors
Vuyyuru SK; Rieder F; Solitano V; Nguyen TM; Crowley E; Narula N; Singh S; Ma C; Jairath V
Journal
The American Journal of Gastroenterology, Vol. 118, No. 7, pp. 1285–1288
Publisher
Wolters Kluwer
Publication Date
July 2023
DOI
10.14309/ajg.0000000000002215
ISSN
0002-9270