Journal article
Lithium and melatonin in pigmented eye rats: Effects of dose and time of day
Abstract
Lithium has been suggested to exert some of its theraputic effects by modifying the function of the retinal-hypothalamic pineal pathway that is essential for the chronobiology of an organism (Seggie et al., 1983). Previous work was done in Wistar rats, an Albino species which lacks the enzyme for synthesis of eye pigment. This pigment is important in the regulation of light cued rhythms. The present project investigated effects of lithium in a …
Authors
Seggie J; Werstiuk ES; Grota L; Joshi M; Brown GM
Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 8, No. 4-6, pp. 733–736
Publisher
Elsevier
Publication Date
January 1984
DOI
10.1016/0278-5846(84)90048-4
ISSN
0278-5846