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A multiplexed, next generation sequencing platform...
Journal article

A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2

Abstract

Population scale sweeps of viral pathogens, such as SARS-CoV-2, require high intensity testing for effective management. Here, we describe “Systematic Parallel Analysis of RNA coupled to Sequencing for Covid-19 screening” (C19-SPAR-Seq), a multiplexed, scalable, readily automated platform for SARS-CoV-2 detection that is capable of analyzing tens of thousands of patient samples in a single run. To address strict requirements for control of …

Authors

Aynaud M-M; Hernandez JJ; Barutcu S; Braunschweig U; Chan K; Pearson JD; Trcka D; Prosser SL; Kim J; Barrios-Rodiles M

Journal

Nature Communications, Vol. 12, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41467-021-21653-y

ISSN

2041-1723