Journal article
Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial
Abstract
AIMS: The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) with reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity in post-discharge outcomes with aliskiren in patients with and without baseline diabetes mellitus (DM).
Authors
Maggioni AP; Greene SJ; Fonarow GC; Böhm M; Zannad F; Solomon SD; Lewis EF; Baschiera F; Hua TA; Gimpelewicz CR
Journal
European Heart Journal, Vol. 34, No. 40, pp. 3117–3127
Publisher
Oxford University Press (OUP)
Publication Date
October 2, 2013
DOI
10.1093/eurheartj/eht342
ISSN
0195-668X