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Prevalence and Significance of Alterations in...
Journal article

Prevalence and Significance of Alterations in Cardiac Structure and Function in Patients With Heart Failure and a Preserved Ejection Fraction

Abstract

BACKGROUND: The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether these alterations in structure and function were associated with cardiovascular morbidity and mortality. METHODS AND RESULTS: The Irbesartan in HFPEF trial (I-PRESERVE) enrolled 4128 patients; echocardiographic …

Authors

Zile MR; Gottdiener JS; Hetzel SJ; McMurray JJ; Komajda M; McKelvie R; Baicu CF; Massie BM; Carson PE

Journal

Circulation, Vol. 124, No. 23, pp. 2491–2501

Publisher

Wolters Kluwer

Publication Date

December 6, 2011

DOI

10.1161/circulationaha.110.011031

ISSN

0009-7322