Journal article
Leukapheresis and low-dose chemotherapy do not reduce early mortality in acute myeloid leukemia hyperleukocytosis: A systematic review and meta-analysis
Abstract
The role of leukapheresis and low-dose chemotherapy is unclear in decreasing early mortality in acute myeloid leukemia (AML) patients with hyperleukocytosis. This systematic review was conducted to describe early mortality (deaths during first induction) in patients with AML with an initial white blood count≥100×10(9)L(-1) stratified by the approach to leukapheresis and hydroxyurea/low-dose chemotherapy. Twenty-one studies were included. …
Authors
Oberoi S; Lehrnbecher T; Phillips B; Hitzler J; Ethier M-C; Beyene J; Sung L
Journal
Leukemia Research, Vol. 38, No. 4, pp. 460–468
Publisher
Elsevier
Publication Date
April 2014
DOI
10.1016/j.leukres.2014.01.004
ISSN
0145-2126