Journal article
Phase 3 Trials of Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for 1 to 4 Brain Metastases: Individual Patient Data Meta-Analysis
Abstract
PURPOSE: To perform an individual patient data (IPD) meta-analysis of randomized controlled trials evaluating stereotactic radiosurgery (SRS) with or without whole-brain radiation therapy (WBRT) for patients presenting with 1 to 4 brain metastases.
METHOD AND MATERIALS: Three trials were identified through a literature search, and IPD were obtained. Outcomes of interest were survival, local failure, and distant brain failure. The treatment …
Authors
Sahgal A; Aoyama H; Kocher M; Neupane B; Collette S; Tago M; Shaw P; Beyene J; Chang EL
Journal
International Journal of Radiation Oncology • Biology • Physics, Vol. 91, No. 4, pp. 710–717
Publisher
Elsevier
Publication Date
March 2015
DOI
10.1016/j.ijrobp.2014.10.024
ISSN
0360-3016