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Early life predictive markers of liver disease...
Journal article

Early life predictive markers of liver disease outcome in an International, Multicentre Cohort of children with Alagille syndrome

Abstract

BACKGROUND & AIMS: Liver disease in Alagille syndrome is highly variable. Many of the patients presenting with severe cholestasis early in life improve spontaneously; 10-20%, however, have progressive disease. It is currently not possible to predict long-term hepatic outcomes in Alagille syndrome. This international, multicentre study was aimed at identifying early life predictors of liver disease outcome. METHODS: Retrospective clinical, …

Authors

Mouzaki M; Bass LM; Sokol RJ; Piccoli DA; Quammie C; Loomes KM; Heubi JE; Hertel PM; Scheenstra R; Furuya K

Journal

Liver International, Vol. 36, No. 5, pp. 755–760

Publisher

Wiley

Publication Date

May 2016

DOI

10.1111/liv.12920

ISSN

0106-9543