Journal article
Single nucleotide polymorphism in IL1B is associated with infection risk in paediatric acute myeloid leukaemia
Abstract
We evaluated single nucleotide polymorphisms (SNPs) associated with infection risk in children with newly diagnosed acute myeloid leukaemia (AML). We conducted a multicentre, prospective cohort study that included children aged ≤18 years with de novo AML. DNA was isolated from blood lymphocytes or buccal swabs, and candidate gene SNP analysis was conducted. Primary outcome was the occurrence of microbiologically documented sterile site …
Authors
Sung L; Dix D; Cellot S; Gillmeister B; Ethier MC; Roslin NM; Johnston DL; Feusner J; Mitchell D; Lewis V
Journal
Clinical Microbiology and Infection, Vol. 22, No. 6, pp. 563.e9–563.e17
Publisher
Elsevier
Publication Date
June 2016
DOI
10.1016/j.cmi.2016.02.006
ISSN
1198-743X