Journal article
Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation: a systematic review and network meta-analysis of randomized controlled trials.
Abstract
INTRODUCTION: Atrial fibrillation (AF) is one of the leading causes of stroke. Risks associated with oral anticoagulation (OAC) limit adherence to recommended therapy. Left atrial appendage (LAA) occlusion is a treatment alternative in patients with AF. We performed a network meta-analysis (NMA) of randomized trials evaluating the efficacy of LAA occlusion compared with oral anticoagulant, antiplatelet, and placebo for stroke prevention. We …
Authors
Hanif H; Belley-Cote EP; Alotaibi A; Dvirnik N; Neupane B; Beyene J; Eikelboom JW; Holmes D; Whitlock RP
Journal
The Journal of Cardiovascular Surgery, Vol. 59, No. 1, pp. 128–139
Publisher
Edizioni Minerva Medica
Publication Date
February 2018
DOI
10.23736/s0021-9509.17.09824-x
ISSN
0021-9509