Journal article
Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis
Abstract
BackgroundThe pathogenesis of pancreatic ductal adenocarcinoma (PDAC) involves multi-stage development of molecular aberrations affecting signaling pathways that regulate cancer growth and progression. This study was performed to gain a better understanding of the abnormal signaling that occurs in PDAC compared with normal duct epithelia.MethodsWe performed immunohistochemistry on a tissue microarray of 26 PDAC, 13 normal appearing adjacent …
Authors
Pham N-A; Schwock J; Iakovlev V; Pond G; Hedley DW; Tsao M-S
Journal
BMC Cancer, Vol. 8, No. 1,
Publisher
Springer Nature
Publication Date
December 2008
DOI
10.1186/1471-2407-8-43
ISSN
1471-2407