Journal article
Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions
Abstract
Fluorescence photobleaching and photoproduct formation were investigated during δ-aminolevulinic acid (ALA) induced protoporphyrin IX (PpIX) PDT of MLL cells in vitro. Cells were incubated in either 0.1 or 1.0 mM ALA for 4 h and were treated with 532 nm or 635 nm light under well oxygenated or hypoxic conditions. Fluorescence spectra were acquired during treatment. Photobleaching and photoproduct formation were quantified using singular value …
Authors
Dysart JS; Patterson MS
Journal
Photochemical & Photobiological Sciences, Vol. 5, No. 1, pp. 73–81
Publisher
Springer Nature
Publication Date
January 2006
DOI
10.1039/b511807g
ISSN
1474-905X