Journal article
Comparison of noninvasive photodynamic therapy dosimetry methods using a dynamic model of ALA-PDT of human skin
Abstract
A numerical model of ALA photodynamic therapy of human skin was used to calculate photosensitizer fluorescence and singlet-oxygen luminescence (SOL) observable at the skin surface during treatment. From the emissions, three practical dose metrics were calculated: the fractional fluorescence bleaching metric (FFBM) given by F(0)/F, where F is photosensitizer protoporphyrin IX (PpIX) fluorescence and F(0) is its initial value, the absolute …
Authors
Liu B; Farrell TJ; Patterson MS
Journal
Physics in Medicine and Biology, Vol. 57, No. 3, pp. 825–841
Publisher
IOP Publishing
Publication Date
February 7, 2012
DOI
10.1088/0031-9155/57/3/825
ISSN
0031-9155