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Effect of 1O2 quencher depletion on the efficiency...
Journal article

Effect of 1O2 quencher depletion on the efficiency of photodynamic therapy

Abstract

Al(iii) phthalocyanine chloride tetrasulfonic acid (AlPcS4) fluorescence and photodynamic oxygen consumption were monitored during AlPcS4-photodynamic therapy (PDT) of Mat LyLu cells in suspension. These measurements were used to calculate the PDT efficiency, which is defined as the oxygen consumption rate divided by the sensitizer concentration. As a function of the intracellular oxygen concentration consumed by PDT, the normalized PDT …

Authors

Weston MA; Patterson MS

Journal

Photochemical & Photobiological Sciences, Vol. 13, No. 1, pp. 112–121

Publisher

Springer Nature

Publication Date

January 2013

DOI

10.1039/c3pp50258a

ISSN

1474-905X