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Validation and Application of a Model of Oxygen...
Journal article

Validation and Application of a Model of Oxygen Consumption and Diffusion During Photodynamic Therapy In Vitro

Abstract

The photophysical parameters for the photosensitizer Pd(II) meso-Tetra(4-carboxyphenyl) porphine (PdT790) acquired in a previous study were incorporated into the PDT oxygen diffusion models for cell suspensions and cell monolayers. The time-dependent phosphorescence signals generated by the diffusion models are shown to match signals previously measured by M.A.W. and M.S.P. when reasonable physical and photophysical parameters are used. …

Authors

Weston MA; Patterson MS

Journal

Photochemistry and Photobiology, Vol. 90, No. 6, pp. 1359–1367

Publisher

Wiley

Publication Date

11 2014

DOI

10.1111/php.12320

ISSN

0031-8655