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GENETIC STUDY: The dopamine D4 Receptor (DRD4)...
Journal article

GENETIC STUDY: The dopamine D4 Receptor (DRD4) gene exon III polymorphism, problematic alcohol use and novelty seeking: direct and mediated genetic effects

Abstract

The present study sought to integrate convergent lines of research on the associations among the dopamine D(4) receptor (DRD4) gene, novelty seeking and drinking behaviors with the overall goal of elucidating genetic influences on problematic drinking in young adulthood. Specifically, this study tested a model in which novelty seeking mediated the relationship between DRD4 variable number of tandem repeats (VNTR) genotype and problematic …

Authors

Ray LA; Bryan A; MacKillop J; McGeary J; Hesterberg K; Hutchison KE

Journal

Addiction Biology, Vol. 14, No. 2, pp. 238–244

Publisher

Wiley

Publication Date

April 2009

DOI

10.1111/j.1369-1600.2008.00120.x

ISSN

1355-6215