Journal article
Perseveration without hyperlocomotion in a spontaneous alternation task in rats sensitized to the dopamine agonist quinpirole
Abstract
Behavioral sensitization induced by intermittent injections of the dopamine agonist quinpirole is characterized by hyperlocomotion and perseveration. This study tested whether in sensitized rats, the expression of perserverative behavior can be independent of hyperlocomotion. Rats received 10 injections of either quinpirole (0.5 mg/kg) or saline in a T-maze apparatus, a procedure that induced locomotor sensitization in the drugged animals. When …
Authors
Einat H; Szechtman H
Journal
Physiology & Behavior, Vol. 57, No. 1, pp. 55–59
Publisher
Elsevier
Publication Date
January 1995
DOI
10.1016/0031-9384(94)00209-n
ISSN
0031-9384