Journal article
Psychostimulant-Induced Behavior as an Animal Model of Obsessive-Compulsive Disorder: An Ethological Approach to the Form of Compulsive Rituals
Abstract
Rats treated chronically with the D2/D3 dopamine receptor agonist quinpirole show a pattern of behavior that meets a set of ethologically derived criteria of compulsive behavior in obsessive-compulsive disorder (OCD). Moreover, in both quinpirole-treated rats and OCD patients, the structure of compulsive rituals appear similar in being composed of relatively few motor acts that are organized in a flexible yet recurrent manner. In addition, the …
Authors
Eilam D; Szechtman H
Journal
CNS Spectrums, Vol. 10, No. 3, pp. 191–202
Publisher
Cambridge University Press (CUP)
Publication Date
March 2005
DOI
10.1017/s109285290001004x
ISSN
1092-8529