Journal article
Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD)
Abstract
RationaleAcute administration of serotonergic agonist, meta-chlorophenylpiperazine (mCPP), attenuates performance of compulsive checking in an animal model of obsessive-compulsive disorder (OCD). It is not known whether mCPP has a similar effect on development of compulsive checking.ObjectivesThe objective of the study was to examine whether similar mechanisms mediate the development versus the performance of compulsive checking in the rat …
Authors
Tucci MC; Dvorkin-Gheva A; Sharma R; Taji L; Cheon P; Peel J; Kirk A; Szechtman H
Journal
Psychopharmacology, Vol. 231, No. 18, pp. 3707–3718
Publisher
Springer Nature
Publication Date
September 2014
DOI
10.1007/s00213-014-3505-6
ISSN
0033-3158