Leukemia inhibitory factor stimulates muscle glucose uptake by a PI3‐kinase dependent pathway that is maintained in white muscle in obesity (1162.4)

OBJECTIVE: To investigates the metabolic effects of leukemia inhibitory factor (LIF) in mouse skeletal muscle. METHODS: Effects of LIF on muscle glucose transport, palmitate oxidation and cellular signaling were investigated in soleus and extensor digitorum longus (EDL) muscles from chow and highfat diet fed wildtype (WT) mice or chow fed muscle‐specific AMPKα2 kinase‐dead (KD) and suppressors of cytokine signaling (SOCS) 3 muscle‐specific …