Journal article
A19 BACTERIAL PROTEASES INCREASE SENSITIVITY TO DIETARY ANTIGEN THROUGH PAR-2 SIGNALING
Abstract
Microbial-dietary-host interactions are generally homeostatic but when dysfunctional, can incite food sensitivities such as celiac disease in genetically predisposed people. However, the specific pathways involved and sequence of events remain poorly understood. We have previously shown that bacterial metabolism of the common dietary antigen, gluten, affects its immunogenicity. Here we tested whether microbial proteases able to degrade gluten …
Authors
FERNANDEZ AC; McCarville J; Galipeau HJ; Deraison C; BERNIER S; Murray JA; Coombes BK; Ruf W; Blanco JC; Surette M
Journal
Journal of the Canadian Association of Gastroenterology, Vol. 1, No. suppl_2, pp. 31–32
Publisher
Oxford University Press (OUP)
Publication Date
March 1, 2018
DOI
10.1093/jcag/gwy009.019
ISSN
2515-2084