Platform, Basket, and Umbrella Trial Designs: Stakeholder Perspectives of Novel Therapeutics

Advancements in genomic and precision medicine have changed the way oncology clinical trials are designed. Compared to the traditional single tumour-based trial, master protocols, which are often classified as basket, umbrella, or platform trials, conduct studies on multiple subgroups under a single overarching protocol. This paper presents the perspectives of patients, clinicians, public payers, private payers, and industry, which were …