A mass budget for transgenic "Supermice" engineered with extra rat growth hormone genes: evidence for energetic limitation

Genetically engineered "Supermice" (Mus musculus, transgenic strain Tg[MT-1,rGH],Bri2) possess multiple copies of rat growth hormone genes yielding growth rates 220% that of normal mice. To discover how Supermice alter their acquisition and allocation of resources under elevated costs of growth, a resource allocation study was conducted on forty 50-day-old normal and transgenic male mice. Individual dry mass budgets were used to compare rates …