Melatonin: Regulator of Adult Hippocampal Neurogenesis

Hippocampal neurogenesis consists in the generation of new neurons in the dentate gyrus of the adult brain (Kempermann et al., 2004a). Initial reports about the neurogenic process in the hippocampus derived from studies of Joseph Altman in the 1960s (Altman and Das, 1966). Further studies supported the existence of new neurons in the hippocampus during adulthood (Cameron and McKay, 1999; Gage et al., 1998; Gould et al., 1997; Gould and Tanapat, …