From ‘Omics to Multi-omics Technologies: the Discovery of Novel Causal Mediators

Purpose of Review‘Omics studies provide a comprehensive characterisation of a biological entity, such as the genome, epigenome, transcriptome, proteome, metabolome, or microbiome. This review covers the unique properties of these types of ‘omics and their roles as causal mediators in cardiovascular disease. Moreover, applications and challenges of integrating multiple types of ‘omics data to increase predictive power, improve causal inference, …