Journal article
Effects of Atrazine on CYP19 Gene Expression and Aromatase Activity in Testes and on Plasma Sex Steroid Concentrations of Male African Clawed Frogs (Xenopus laevis)
Abstract
Some investigators have suggested that the triazine herbicide atrazine can cause demasculinization of male amphibians via upregulation of the enzyme aromatase. Male adult African clawed frogs (Xenopus laevis) were exposed to three nominal concentrations of atrazine (1, 25, or 250 microg atrazine/l) for 36 days, and testicular aromatase activity and CYP19 gene expression, as well as concentrations of the plasma sex steroids testosterone (T) and …
Authors
Hecker M; Park J-W; Murphy MB; Jones PD; Solomon KR; Van Der Kraak G; Carr JA; Smith EE; du Preez L; Kendall RJ
Journal
Toxicological Sciences, Vol. 86, No. 2, pp. 273–280
Publisher
Oxford University Press (OUP)
Publication Date
August 1, 2005
DOI
10.1093/toxsci/kfi203
ISSN
1096-6080