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Azacitidine Monotherapy in Patients With...
Journal article

Azacitidine Monotherapy in Patients With Treatment-Naïve Higher-risk Myelodysplastic Syndrome: A Systematic Literature Review and Meta-analysis

Abstract

BACKGROUND: The global incidence of myelodysplastic syndromes (MDS) has been estimated as 0.06 to 0.26/100,000. Since their introduction, hypomethylating agents have played a central role in the treatment of MDS, with heterogeneous real-world outcomes. MATERIALS AND METHODS: We assessed and synthesized clinical outcomes of azacitidine (AZA) monotherapy in treatment-naïve patients with higher-risk MDS. A systematic literature review was …

Authors

Hasegawa K; Wei AH; Garcia-Manero G; Daver NG; Rajakumaraswamy N; Iqbal S; Chan RJ; Hu H; Tse P; Yan J

Journal

Clinical Lymphoma Myeloma & Leukemia, Vol. 23, No. 2, pp. 127–137

Publisher

Elsevier

Publication Date

February 2023

DOI

10.1016/j.clml.2022.11.002

ISSN

2152-2650