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Common variants at the MHC locus and at chromosome...
Journal article

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Abstract

Peter Donnelly and colleagues report a genome-wide association study for Barrett's esophagus, a common premalignant condition associated with stomach acid reflux and predisposing to esophageal adenocarcinoma. They identify two loci associated with susceptibility to Barrett's esophagus.

Authors

Su Z; Gay LJ; Strange A; Palles C; Band G; Whiteman DC; Lescai F; Langford C; Nanji M; Edkins S

Journal

Nature Genetics, Vol. 44, No. 10, pp. 1131–1136

Publisher

Springer Nature

Publication Date

October 2012

DOI

10.1038/ng.2408

ISSN

1061-4036