Journal article
A double-edged sword: does highly active antiretroviral therapy contribute to syphilis incidence by impairing immunity to Treponema pallidum?
Abstract
BACKGROUND AND HYPOTHESIS: Recently, the world has experienced a rapidly escalating outbreak of infectious syphilis primarily affecting men who have sex with men (MSM); many are taking highly active antiretroviral therapy (HAART) for HIV-1 infection. The prevailing hypothesis is that HAART availability and effectiveness have led to the perception among both individuals who are HIV-1 infected and those who are uninfected that HIV-1 transmission …
Authors
Rekart ML; Ndifon W; Brunham RC; Dushoff J; Park SW; Rawat S; Cameron CE
Journal
Sexually Transmitted Infections, Vol. 93, No. 5,
Publisher
BMJ
Publication Date
August 2017
DOI
10.1136/sextrans-2016-052870
ISSN
1368-4973