Journal article
Skeletal muscle-endothelial cell cross talk through angiotensin II
Abstract
The role of angiotensin II (ANG II) in postnatal vasculogenesis and angiogenesis during skeletal muscle (SKM) regeneration is unknown. We examined the capacity of ANG II to stimulate capillary formation and growth during cardiotoxin-induced muscle regeneration in ACE inhibitor-treated ANG II type 1a receptor knockout (AT1a(-/-)) and C57Bl/6 control mice. Analysis of tibialis anterior (TA) cross-sections revealed 17% and 23% reductions in …
Authors
Bellamy LM; Johnston APW; De Lisio M; Parise G
Journal
American Journal of Physiology - Cell Physiology, Vol. 299, No. 6, pp. c1402–c1408
Publisher
American Physiological Society
Publication Date
December 2010
DOI
10.1152/ajpcell.00306.2010
ISSN
0363-6143