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Xin Is a Marker of Skeletal Muscle Damage Severity...
Journal article

Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies

Abstract

Xin is a striated muscle-specific protein that is localized to the myotendinous junction in skeletal muscle. However, in injured mouse muscle, Xin expression is up-regulated and observed throughout skeletal muscle fibers and within satellite cells. In this study, Xin was analyzed by immunofluorescent staining in skeletal muscle samples from 47 subjects with various forms of myopathy, including muscular dystrophies, inflammatory myopathies, …

Authors

Nilsson MI; Nissar AA; Al-Sajee D; Tarnopolsky MA; Parise G; Lach B; Fürst DO; van der Ven PFM; Kley RA; Hawke TJ

Journal

American Journal Of Pathology, Vol. 183, No. 6, pp. 1703–1709

Publisher

Elsevier

Publication Date

December 2013

DOI

10.1016/j.ajpath.2013.08.010

ISSN

0002-9440