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Analysis of γ-Carboxyglutamic Acid Content of...
Journal article

Analysis of γ-Carboxyglutamic Acid Content of Protein, Urine, and Plasma by Capillary Electrophoresis and Laser-Induced Fluorescence

Abstract

When the properties of an analyte are known, the separation system can be designed to make the analyte of interest migrate at either a much faster or a much slower velocity compared to other molecules in the sample matrix. A simple and sensitive method to analyze the gamma-carboxyglutamic acid (Gla) content of protein, urine, and plasma was developed using capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The …

Authors

Britz-Mckibbin P; Vo HC; MacGillivray RTA; Chen DDY

Journal

Analytical Chemistry, Vol. 71, No. 8, pp. 1633–1637

Publisher

American Chemical Society (ACS)

Publication Date

April 1, 1999

DOI

10.1021/ac981241g

ISSN

0003-2700