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Metabolomic studies of radiation‐induced apoptosis...
Journal article

Metabolomic studies of radiation‐induced apoptosis of human leukocytes by capillary electrophoresis‐mass spectrometry and flow cytometry: Adaptive cellular responses to ionizing radiation

Abstract

There is growing interest in the development of new methods for elucidating the biological effects of low-dose exposure to ionizing radiation (IR) on human health. Herein, we introduce a strategy for assessment of the impact of radiation-induced oxidative stress on the intra-cellular metabolism of human leukocytes. Untargeted metabolomic analyses were performed by CE-ESI-MS on irradiated leukocytes exposed to increasing doses of -radiation …

Authors

Lee R; Britz‐McKibbin P

Journal

Electrophoresis, Vol. 31, No. 14, pp. 2328–2337

Publisher

Wiley

Publication Date

July 2010

DOI

10.1002/elps.200900451

ISSN

0173-0835