Journal article
Direct analysis of polyols using 3-nitrophenylboronic acid in capillary electrophoresis: thermodynamic and electrokinetic principles of molecular recognition
Abstract
The design of boronic acid sensors for photometric detection of carbohydrates has relied on exploiting differences in the thermodynamic stability of complex formation for molecular recognition. Herein, we introduce a direct method for analysis of sugar alcohols using 3-nitrophenylboronic acid (NPBA) as an electrokinetic probe in capillary electrophoresis (CE). Dynamic complexation of neutral polyols by NPBA during electromigration allows for …
Authors
Fei F; Britz-McKibbin P
Journal
Analytical and Bioanalytical Chemistry, Vol. 398, No. 3, pp. 1349–1356
Publisher
Springer Nature
Publication Date
October 2010
DOI
10.1007/s00216-010-4038-4
ISSN
1618-2642