Journal article
Synthesis and anti-toxoplasmosis activity of 4-arylquinoline-2-carboxylate derivatives
Abstract
A one-step synthesis of 4-arylquinoline-2-carboxylates along with their antiprotozoal activity against the pathogenic parasite Toxoplasma gondii is reported. Mechanistic insights into the role of Lewis acid (silver triflate) versus Bronsted acid (triflic acid) catalysis are revealed clarifying aspects of the mechanism of the quinoline synthesis.
Authors
McNulty J; Vemula R; Bordón C; Yolken R; Jones-Brando L
Journal
Organic & Biomolecular Chemistry, Vol. 12, No. 2, pp. 255–260
Publisher
Royal Society of Chemistry (RSC)
Publication Date
January 14, 2014
DOI
10.1039/c3ob41539b
ISSN
1477-0520