Journal article
Comparison of three cell-based drug screening platforms for HSV-1 infection
Abstract
Acyclovir (ACV) and its derivatives have been highly effective for treating recurrent, lytic infections with Herpes Simplex Virus, type 1 (HSV-1), but searches for additional antiviral drugs are motivated by recent reports of resistance to ACV, particularly among immunocompromised patients. In addition, the relative neurotoxicity of ACV and its inability to prevent neurological sequelae among HSV-1 encephalitis survivors compel searches for new …
Authors
D'Aiuto L; Williamson K; Dimitrion P; McNulty J; Brown CE; Dokuburra CB; Nielsen AJ; Lin WJ; Piazza P; Schurdak ME
Journal
Antiviral Research, Vol. 142, , pp. 136–140
Publisher
Elsevier
Publication Date
June 2017
DOI
10.1016/j.antiviral.2017.03.016
ISSN
0166-3542