Journal article
High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes
Abstract
Iron overload (IO) reflected by elevated ferritin is associated with increased mortality in myelodysplastic syndromes (MDS), however, ferritin is an imperfect metric. Elevated labile plasma iron correlates with clinical outcomes and transferrin saturation (TSAT) >80%, but is not readily measurable. The trajectory of TSAT, and its association with clinical outcomes remain undefined. Canadian MDS registry patients were evaluated. Mean TSAT, mean …
Authors
Teichman J; Geddes M; Zhu N; Keating M-M; Sabloff M; Christou G; Leber B; Khalaf D; St-Hilaire E; Finn N
Journal
Haematologica, Vol. 108, No. 2, pp. 532–542
Publisher
Ferrata Storti Foundation (Haematologica)
DOI
10.3324/haematol.2022.280723
ISSN
0390-6078